Stuart Levine

About

Work

Massachusetts Institute of Technology
|

MIT BioMicro Center Director

US

Whitehead Institute for Biomedical Research
|

Postdoctoral associate / Research Scientist

US

Education

Harvard University
United States of America

PhD

Massachusetts Institute of Technology
United States of America

SB

Publications

Enhancer Reprogramming in Melanoma Immune Checkpoint Therapy Resistance

Summary

preprint

A single-cell liver atlas of Plasmodium vivax infection.

Published by

Cell host & microbe

Summary

journal-article

NExtSEEK: Extending SEEK for Active Management of Interoperable Metadata.

Published by

Journal of biomolecular techniques : JBT

Summary

journal-article

Developmental Deconvolution for Classification of Cancer Origin.

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Cancer discovery

Summary

journal-article

Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells.

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iScience

Summary

journal-article

Developmental Deconvolution for Classification of Cancer Origin

Summary

preprint

Gene signatures and host-parasite interactions revealed by dual single-cell profiling of <i>Plasmodium vivax</i> liver infection

Summary

preprint

Quantitative mapping of the cellular small RNA landscape with AQRNA-seq.

Published by

Nature biotechnology

Summary

journal-article

Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases.

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Science advances

Summary

journal-article

Benchmarking cDNA sequencing on PromethION

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Journal of biomolecular techniques : JBT

Summary

journal-article

Bioinformatics Core Survey Highlights the Challenges Facing Data Analysis Facilities.

Published by

Journal of biomolecular techniques : JBT

Summary

journal-article

Multisite Evaluation of Next-Generation Methods for Small RNA Quantification.

Published by

Journal of biomolecular techniques : JBT

Summary

journal-article

SPRI Beads-based Size Selection in the Range of 2-10kb.

Published by

Journal of biomolecular techniques : JBT

Summary

journal-article

High-throughput Minitaturized RNA-Seq Library Preparation.

Published by

Journal of biomolecular techniques : JBT

Summary

journal-article

Cross-Site Evaluation of Commercial Sanger Sequencing Chemistries.

Published by

Journal of biomolecular techniques : JBT

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journal-article

A set of miniaturized high-throughput library protocols for RNA sequencing

Published by

Journal of biomolecular techniques : JBT

Summary

journal-article

HONEY I SHRUNK THE KITS: Practical Adventures in Reducing Assay Volumes

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Journal of biomolecular techniques : JBT

Summary

journal-article

Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet.

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Cell

Summary

journal-article

Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription.

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Cell chemical biology

Summary

journal-article

Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells.

Published by

BMC cancer

Summary

journal-article

Global transcriptional regulation of innate immunity by ATF-7 in C. elegans.

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PLoS genetics

Summary

journal-article

Cross Site Evaluation of Sanger Sequencing Dye Chemistries

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Journal of biomolecular techniques : JBT

Summary

journal-article

GBIRG Bioinformatics Core Survey Highlights the Challenges Facing Data Analysis Facilities

Published by

Journal of biomolecular techniques : JBT

Summary

journal-article

Miniaturization of Illumina Library Preparation for High Throughput, Plate-Based Next Generation Sequencing Studies

Published by

Journal of biomolecular techniques : JBT

Summary

journal-article

Sequencing-based quantitative mapping of the cellular small RNA landscape

Summary

preprint

Single-cell transcriptomic profiling of the aging mouse brain.

Published by

Nature neuroscience

Summary

journal-article

H3K27me3-mediated silencing of structural genes is required for zebrafish heart regeneration.

Published by

Development (Cambridge, England)

Summary

journal-article

HRI coordinates translation necessary for protein homeostasis and mitochondrial function in erythropoiesis.

Published by

eLife

Summary

journal-article

Global transcriptional regulation of innate immunity in C. elegans

Summary

other

Iron and Heme Coordinate Erythropoiesis through HRI-Mediated Regulation of Protein Translation and Gene Expression

Summary

other

Single-cell transcriptomics of the aged mouse brain reveals convergent, divergent and unique aging signatures

Summary

preprint

In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites.

Published by

Cell host & microbe

Summary

journal-article

Cross-site comparison of ribosomal depletion kits for Illumina RNAseq library construction.

Published by

BMC genomics

Summary

journal-article

Cross-Site Comparison of Ribosomal Depletion Kits for Illumina RNAseq Library Construction

Summary

other

Host proteostasis modulates influenza evolution.

Published by

eLife

Summary

journal-article

The Hox proteins Ubx and AbdA collaborate with the transcription pausing factor M1BP to regulate gene transcription.

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The EMBO journal

Summary

journal-article

Mutational spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellular carcinoma.

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Proceedings of the National Academy of Sciences of the United States of America

Summary

journal-article

Monitoring Error Rates In Illumina Sequencing.

Published by

Journal of biomolecular techniques : JBT

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journal-article

RNA polymerase II promoter-proximal pausing in mammalian long non-coding genes.

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Genomics

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journal-article

Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo.

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Nucleic acids research

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journal-article

Transportable, Chemical Genetic Methodology for the Small Molecule-Mediated Inhibition of Heat Shock Factor 1.

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ACS chemical biology

Summary

journal-article

Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences.

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Nature communications

Summary

journal-article

TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release.

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Nature structural & molecular biology

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journal-article

Arsenic exposure perturbs the gut microbiome and its metabolic profile in mice: an integrated metagenomics and metabolomics analysis.

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Environmental Health Perspectives

Summary

journal-article

Diverse cell stresses induce unique patterns of tRNA up- and down-regulation: tRNA-seq for quantifying changes in tRNA copy number.

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Nucleic acids research

Summary

journal-article

Polycomb Repressive Complex 2 regulates lineage fidelity during embryonic stem cell differentiation.

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PloS one

Summary

journal-article

H2A.Z acidic patch couples chromatin dynamics to regulation of gene expression programs during ESC differentiation.

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PLoS genetics

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journal-article

Which RNA-Seq Processing Algorithm Should I Pick? A Comparison of RNA-Seq Pipelines Based on Experimental Design, Sample Properties and Sequencing Technology.

Published by

Journal of biomolecular techniques : JBT

Summary

journal-article

Gut microbiome perturbations induced by bacterial infection affect arsenic biotransformation.

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Chemical research in toxicology

Summary

journal-article

Lane-by-lane sequencing using Illumina's Genome Analyzer II.

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BioTechniques

Summary

journal-article

Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity.

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Proceedings of the National Academy of Sciences of the United States of America

Summary

journal-article

Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage.

Published by

Cell

Summary

journal-article

Comparison of SYBR Enzymes and Standards in Illumina Library Quantification.

Published by

Journal of biomolecular techniques : JBT

Summary

journal-article

miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity.

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Nature neuroscience

Summary

journal-article

Mediator and cohesin connect gene expression and chromatin architecture.

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Nature

Summary

journal-article

Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells.

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Genes & development

Summary

journal-article

Effects of age on meiosis in budding yeast.

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Developmental cell

Summary

journal-article

H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment.

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Cell

Summary

journal-article

Divergent transcription from active promoters.

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Science (New York, N.Y.)

Summary

journal-article

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.

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Genes & development

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journal-article

Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells.

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Cell

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journal-article

A chromatin landmark and transcription initiation at most promoters in human cells.

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Cell

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journal-article

Foxp3 occupancy and regulation of key target genes during T-cell stimulation.

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Nature

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journal-article

Control of developmental regulators by Polycomb in human embryonic stem cells.

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Cell

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journal-article

Polycomb complexes repress developmental regulators in murine embryonic stem cells.

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Nature

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journal-article

Genome-wide map of nucleosome acetylation and methylation in yeast.

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Cell

Summary

journal-article

The core centromere and Sgo1 establish a 50-kb cohesin-protected domain around centromeres during meiosis I.

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Genes & development

Summary

journal-article

Core transcriptional regulatory circuitry in human embryonic stem cells.

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Cell

Summary

journal-article

Division of labor in polycomb group repression.

Published by

Trends in biochemical sciences

Summary

journal-article

Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus.

Published by

Molecular cell

Summary

journal-article

The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.

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Molecular and cellular biology

Summary

journal-article